[[Macula Densa]]: Senses changes in sodium ion concentration in the tubular fluid and regulates the release of renin from the granular cells
[[Granular Cell]]: Synthesizes and secretes [[Renin]]
[[Mesangial Cell]]: Has supportive, contractile, and phagocytic functions
The afferent arteriole and efferent arteriole accompany the distal convoluted tubule, growing together outside the renal capsule.
When the macula densa senses changes in the sodium ion concentration of the afferent arteriole, it regulates the amount of renin secreted by the granular cells. Renin then regulates the tension of the mesangial cells, thereby playing a role in regulating the blood flow of the afferent arteriole (autoregulation).
