Cardiac Injury and Myocardial Infarction Test Indicators (Myocardial Enzyme Spectrum)

  • Myocardial Enzyme Spectrum
      • [[Lactate Dehydrogenase]]
    • [[Creatine Kinase and Isoenzymes CK]]: Not as sensitive as cTnI; if cTnI elevation is caused by non-myocardial infarction (such as infection, heart failure, etc.), CKMB will not rise. Combined, they better determine whether it is myocardial infarction.
    • [[Aspartate Aminotransferase]] (less used)
    • [[α-Hydroxybutyrate Dehydrogenase]] (less used)
  • [[Cardiac Troponin cTnI]]
  • [[Myoglobin]] (less used)
  • [[B-type Natriuretic Peptide BNP]]
Symptom - Detection Time Gap Peak Time Duration Sensitivity Specificity
Creatine Kinase MB (CK-MB) 3 - 4 hours 24 hours 3 - 4 days +++ +++
Troponin T (Troponin T) 3 - 4 hours 2 - 3 days 7 - 14 days +++++ +++++
Troponin I (Troponin I) 3 - 4 hours 2 - 3 days 5 - 7 days +++++ +++++
High-sensitivity Troponin (hs-TnT or I) 1 - 3 hours 2 - 3 days - ++++ +++

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