Physiology and Pathology of Urine Volume

Urine Volume Physiological Pathological
[[Polyuria]] >2500ml/24h Large amount of water intake in a short time or consumption of foods and drinks with diuretic effects (tea, coffee) and use of diuretics or drugs with diuretic effects 1. Endocrine and metabolic disorders (diabetes, diabetes insipidus).
2. Kidney diseases with concentration dysfunction (chronic nephritis, chronic membranous nephritis, chronic interstitial nephritis, polyuric phase of acute renal failure).
3. Psychogenic polyuria.
[[Oliguria]] <500ml/24h or 17ml/h Normal humans need at least 400-500ml of water daily to saturate and dissolve metabolic wastes for excretion 1. Prerenal: decreased blood volume, reduced renal blood flow
2. Renal: parenchymal damage :right_arrow: decreased glomerular filtration membrane permeability, decreased total glomerular filtration area, tubular structural and functional damage
3. Postrenal: obstruction of urine outflow through ureter, bladder, urethra

If urine remains close to saturation for a long time, stones and casts are easily precipitated.
[[Anuria]] <100ml/24h or complete absence of urine within 12h
[[Urinary Retention]] Inability to urinate