Learning about fluid therapy, I found I don’t understand acid-base imbalance.
Learning about acid-base imbalance, I found I don’t know how to interpret blood gas.
Learning about blood gas analysis, I found this video explaining the oxygen dissociation curve, starting from the most basic biochemistry.
https://www.bilibili.com/video/BV1XT421X7RG/
Notes
| Left Shift (e.g., lungs) | Right Shift (e.g., muscles) | |
|---|---|---|
| Temperature | ↓ (lungs ventilate) | ↑ (heat produced by metabolism) |
| Carbon dioxide | ↓ (CO2 exhaled) | ↑ (CO2 produced) |
| 2,3-DPG | ↓ | ↑ |
| pH | ↑ (decreased CO2 in exhalation) | ↓ (acidic metabolic products) |
As for how these factors affect the left or right shift of the oxygen dissociation curve, it is too complex; please refer to the tutorial.